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STANDARD OPERATING PROCEDURE FOR AN IN VITRO BIOACCESSIBILITY ASSAY FOR LEAD AND ARSENIC IN SOIL
U.S. EPA, Office of Land and Emergency Management. OLEM 9200.2-164, 33 pp, 20 Apr 2017

The purpose of this standard operating procedure (SOP) is to define the proper analytical procedure for the validated in vitro bioaccessibility (IVBA) assay for lead and arsenic in soil, to describe the typical working range and limits of the assay and quality assurance factors, and to indicate potential interferences. The method has been validated only for lead and arsenic in soil, not other contaminants or matrices (e.g., water, air, amended soils, dust, food, etc.). This SOP is intended to be used as a reference for developing site-specific quality assurance project plans and sampling and analysis plans. https://semspub.epa.gov/work/HQ/196750.pdf



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