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VALIDATION ASSESSMENT OF IN VITRO ARSENIC BIOACCESSIBILITY ASSAY FOR PREDICTING RELATIVE BIOAVAILABILITY OF ARSENIC IN SOILS AND SOIL-LIKE MATERIALS AT SUPERFUND SITES
U.S. EPA, Office of Land and Emergency Management. OLEM 9355.4-29, 25 pp, 20 Apr 2017

This report summarizes the basis for EPA's determination that the in vitro bioaccessibility (IVBA) method for arsenic has satisfied the validation and regulatory acceptance criteria for application of the method in an appropriate regulatory context. The arsenic method estimates site-specific relative bioavailability (RBA) of arsenic in soils quickly and inexpensively relative to in vivo methods and is well suited for regulatory use in arsenic risk assessment. https://semspub.epa.gov/work/HQ/196751.pdf.



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